职位描述
主要职责:
1. 负责蛋白药物的结构表征方法的分析,包括但不限于分子量、肽图、二硫键等;
2. 负责强降解研究,包括但不限于方案制定、样品制备、数据分析和报告撰写;
3. 负责电荷异构体的结构成因与功能研究,包括但不限于方案制定、样品制备、数据分析和报告撰写;
4. 负责UPLC肽图放行方法的开发与验证,包括但不限于开发、验证、放行检测和异常调查;
Responsibilities:
1. Responsible for structural characterization method analysis of protein drugs, including but not limited to molecular weight determination, peptide mapping, disulfide bond analysis, etc.
2. Responsible for forced degradation studies, including but not limited to protocol development, sample preparation, data analysis, and report writing.
3. Responsible for investigating the structural causes and functional impact of charge variants, including but not limited to protocol development, sample preparation, data analysis, and report writing.
4. Responsible for the development, validation, and release testing of UPLC peptide mapping methods, including method development, validation, release testing.