制剂高级研究员/经理/副总监(J13361)
2026-06-29
凯莱英生物· 上海·
凯
ADC研究员/首席研究员 ADC Scientist / Principal ADC Scientist(J12465)
凯莱英生物| 上海
社招本科
发布于 2025-09-27
职位描述
Develop conjugation (cysteine/lysine/enzymatic) for ADCs; optimize parameters (kinetics, stoichiometry) for DAR/purity/stability;
Develop purification (CEX, AEX, HIC, AC) for crude ADC;
Scale-up conjugation (bench to 100L+); prepare tech transfer docs.
Support CMC on formulation, analytics & IND/BLA.
任职要求
PhD in Biochemistry/Chemical Biology 1 yr ADC experience, or 3 yrs ADC conjugation development.
Conjugation & Purification with ≥2 methods (e.g., cysteine, THIOMAB™, enzyme) & ≥2 purification (e.g., TFF, CEX, HIC)
Process Development with cGMP/ICH scale-up experience (DOE/QbD)